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New study > Long-term Results > Laparoscopic Nissen fundoplication > Anti-reflux Surgery > Massachusetts General Hospital > Harvard Medical School > Minimally invasive procedure > Gastroesophageal reflux disease GERD > Seventy-one percent of patients satisfied with long-term results > Primary or revision redo laparoscopic fundoplication > By single surgeon > Near normal scores of GERD−HRQL Health-Related Quality of Life Scale

Does the results of this study demonstrate that most patients undergoing primary laparoscopic fundoplication have near normal GERD−HRQL scores? Are the patients satisfied with their decision to undergo surgery at long-term follow-up? Are the results following redo laparoscopic fundoplication as good as with primary laparoscopic fundoplication?

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…Patients undergoing laparoscopic fundoplication (anti-reflux surgery) by experienced surgeons appear to be satisfied with the decision to undergo surgery and have low re-operation rates, according to a report in the May issue of Archives of Surgery, one of the JAMA/Archives journals.

Laparoscopic fundoplication is a minimally invasive procedure to correct gastroesophageal reflux disease (GERD). Although studies show the short-term effectiveness of laparoscopic anti-reflux surgery, results of longer-term studies have varied.

Denise W. Gee, MD, of Massachusetts General Hospital and Harvard Medical School, Boston, and colleagues studied 191 patients who underwent primary or revision (redo) laparoscopic fundoplication by a single surgeon from 1997 to 2006. Surveys were mailed to participants to evaluate their symptoms on the GERD−Health-Related Quality of Life Scale (HRQL), which has a score of zero to 45 (with zero representing no symptoms). Use of post-operative anti-reflux medication, the need for post-operative intervention, patient satisfaction and patient willingness to have the operation again were also assessed.

Participants (average age 52) were 60 percent female and 40 percent male. “The median [midpoint] duration of follow-up was 60 months,” the authors write. Of all 191 participants, 173 patients had primary anti-reflux surgery and 18 patients had redo anti-reflux surgery. The average GERD score for those undergoing primary anti-reflux surgery was lower than that of patients who had redo anti-reflux surgery (5.71 vs. 14.25 after surgery).

Seventy-one percent of patients who underwent primary anti-reflux surgery were satisfied with long-term results, while only 35 percent of those who underwent redo anti-reflux surgery reported being satisfied. The majority of patients, 88 percent of those who underwent primary anti-reflux surgery and 76 percent of those who had redo anti-reflux surgery, stated they would be willing to have the surgery again.

“Only three patients (1.2 percent) required re-operation,” the authors write. “Patients with body mass indexes (BMIs) between 25 and 35 had lower GERD-HRQL scores than thin and morbidly obese patients.”

“In contrast to reports in the medical literature, the results of this study demonstrate that most patients undergoing primary laparoscopic fundoplication by an experienced surgical team have near normal GERD−HRQL scores at long-term follow-up and low re-operation rates and are satisfied with their decision to undergo surgery. In addition, BMI appears to be an important factor when predicting long-term outcomes,” the authors conclude. “Results following redo laparoscopic fundoplication are not as good, highlighting the importance of proper patient selection and surgical technique when performing primary laparoscopic fundoplication.”