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Category Archives: Unmet needs in gastrointestinal diseases

Stented sleeve implant limits digestion > Device goes down the esophagus into the stomach > Experiment in treating morbid obesity especially in type 2 diabetics > Proximal fixation may prevent migration > Natural Orifices Endoscopic Transluminal Surgery NOTES device > Prior to gastric bypass surgery such as Roux-en-Y Gastric Bypass or Laparoscopic Adjustable Gastric Banding > EndoBarrier device > GI Dynamics

Wednesday, November 5, 2008

Does the food go on the inside of the endobarrier device with the digestive enzymes on the outside of the device? Does the endobarrier device modify metabolic pathways and prevent the mixing of food and digestive enzymes? Does the EndoBarrier stenting device migrate without safe and secure proximal fixation with T fasteners?

IIP > justin > […]

Filed in Safe and secure proximal fixation, Type 2 diabetics, Experiment in treating morbid obesity, Stented sleeve implant limits digestion, Roux-en-Y gastric bypass, Modify metabolic pathways, Hypertension and pulmonary embolus risk, Adjustable Gastric Banding, Prior too gastric bypass surgery, Stented sleeve implant, Incisionless Surgical Technique, GI Dynamics, Reduced post-operative pain, Gastrointestinal and Minimally Invasive Surgery GMIS, Surgical revision, Prevent the mixing of food and digestive enzymes, Digestive enzymes, Endobarrier device, Lining of a portion of the gastrointestinal tract, Safer alternative to gastric bypass, Incisionless Natural Orifice Surgery, Minimally Invasive Surgery MIS, Investigational device, Navigation inside the stomach and abdominal cavity, Natural Orifice Transgastric Endoscopic Surgery NOTES, Transluminal translumenal procedures, Society of American Gastrointestinal and Endoscopic Sur, Medical Device Company, Polaris Venture Partners, Johnson & Johnson Development Corporation, Food bypasses the duodenum and proximal jejunum, More rapid recovery and lower cost, Applicable to wider range of patients, Reversible procedure, Advanced Technology Ventures, Domain Associates, Cutlass Capital, No visible skin scar, scar-free surgery, Efficacy, Minimally invasive surgery techniques, Incision-less solutions, Long-term graft performance, Natural orifices such as the mouth rectum or vagina, Flexible scope, Food and Drug Administration FDA, Flexible endoscopes that have working channels, Using transoral access, Unmet needs in gastrointestinal diseases, Flexible endoscope, Bodies' natural orifices, Natural orifice transluminal endoscopic surgery, High blood pressure, Transoral treatment method, Less-invasive, T fasteners, New suture anchor, Minimally invasive approach, No CPT code, Likely to be widely adopted, organ resections, Diabetes, Reduced risk of adhesions, Entrepreneurs and investors, Venture Capital Financing, Clinical and physiologic patterns, Natural Orifice Transluminal Endoscopic Surgery NOTES, flexible endoscopic sleeve open at both ends, Tie-knot device approximates the suture ends, Gastrotomy, Substantial learning curve, Innovative Hybrid T-fasteners, endoluminal bariatric surgery, Bariatric sleeve, endoscopic gastric reduction, No Scar Surgery | Comments Off

Bard EndoCinch endosuturing system > Long-term outcome > Endoluminal gastroplication > Treatment of gastro-oesophageal reflux disease > Effect of a second procedure > Gastroenterology > University Hospital of North Norway

Thursday, October 23, 2008

Does the development of innovative NOTES devices for improving the function of the lower esophageal sphincter LES continue? What role will Polymethylmethacrylate PMMA beads play in the thicken of the tissue and the strengthen of the LES when the microbeads are implanted in local tissue adjacent to the LES? Will the promising work in Endoscopic […]

Filed in American Society for Gastrointestinal Endoscopy ASGE, Gastroesophageal reflux disease GERD, Barrett's esophagus, Oregon Health and Science University, Anchor plications, External Accessory Channel EAC, Endoluminal gastroplication ELGP, Enteryx Polymer Enteric Medical Technologies, Polymethylmethacrylate PMMA, NoScarSurgeons.com, Gastrointestinal and Minimally Invasive Surgery GMIS, Boston Scientific, StomaphyX EndoGastric Solutions, No CPT code, Medtronic, home by the day after surgery, Incisionless Surgical Technique, Clinical and physiologic patterns, Reduced risk of adhesions, ESD endoscopically assisted endoluminal suturing device, Full-Thickness Plicator, Endoscopic Suturing for Gastroesophageal Reflux Disease, Society of American Gastrointestinal and Endoscopic Sur, Endoscopy Endoscopic, Medical Device Development, Endoluminal Radiofrequency Ablation of Barrett's Esopha, ESD-5 including the Sew Right Device and Tie Knot Devic, Medical Universities Research Institutes Med Societies, EndoCinch BARD Endoscopic Technologies, NDO surgical Mansfield MA, Medical Device Company, Endoluminal Endolumenal Hollow Vessel, Transmural injections of ENTERYX, Endoscopic Gastroplasty devices, Endoscopically mediated endoluminal device, New treatment methods and devices, Lee Swanstrom, NOTES & NEWS, Incisionless Natural Orifice Surgery, Minimally Invasive Surgery MIS, EndoCinch Bard Davol Inc, Endoscopic suturing, Natural orifices such as the mouth rectum or vagina, Incision-less solutions, Unmet needs in gastrointestinal diseases, Pioneer in Natural Orifice Surgery, NOTES techniques, Flexible endoscopes that have working channels, Stapler for flexible endoscopes, No scar anti reflux procedure, Treatment of Gastroesophageal Reflux Disease GERD, Less-invasive, Lengthening of the esophagus, Bodies' natural orifices, NOTES, Natural orifice transluminal endoscopic surgery, Flexible endoscope, Initial applications of NOTES, Treat GERD, Symptoms of GERD, NOTES fundoplication procedure, Flexible scope, Minimally invasive approach, Natural Orifice Transluminal Endoscopic Surgery NOTES, endoscopic suturing device, EndoGastric Solutions Inc Redmond WA, EsoPhyx endoluminal fundoplication, per-oral transgastric, Stretta device, EsophyX EndoGastric Solutions, Wilson-Cook endoscopic suturing device, NDO Plicator, PMMA beads, Gatekeeper reflux repair system Medronic Shoreview MN, Stretta procedure, GERD, Substantial learning curve, Curon Medical, Tightening of LES, multiple endocinch like PTFE sutures being passed, Wilson-Cook Medical Winstom Salem NC, prevention of reflux, No Scar Surgery | Comments Off

New study > Long-term Results > Laparoscopic Nissen fundoplication > Anti-reflux Surgery > Massachusetts General Hospital > Harvard Medical School > Minimally invasive procedure > Gastroesophageal reflux disease GERD > Seventy-one percent of patients satisfied with long-term results > Primary or revision redo laparoscopic fundoplication > By single surgeon > Near normal scores of GERD−HRQL Health-Related Quality of Life Scale

Tuesday, May 27, 2008

Does the results of this study demonstrate that most patients undergoing primary laparoscopic fundoplication have near normal GERD−HRQL scores? Are the patients satisfied with their decision to undergo surgery at long-term follow-up? Are the results following redo laparoscopic fundoplication as good as with primary laparoscopic fundoplication?

IIP > read on here > http://www.endonurse.com…
…Patients undergoing laparoscopic fundoplication […]

Filed in Endolumenal therapy, Laparoscopic Surgical Procedures, General and gastrointestinal surgery, Advance Natural Orifice Surgery NOS, Clinical effectiveness, Establish fast and safe Pneumoperitoneum, Endoscopic Gastroplasty devices, Esophageal adenocarcinoma, Gastroesophageal reflux disease GERD, Anchor plications, Endoluminal gastroplication ELGP, Endoscopic Suturing for Gastroesophageal Reflux Disease, GI conditions, Adoption rates for laparoscopic surgery, Primary or revision redo laparoscopic fundoplication, Seventy-one percent of patients satisfied with long-ter, Single surgeon, Near normal scores, GERD−HRQL Health-Related Quality of Life Scale, Minimally invasive procedure, Laparoscopic Anti-reflux Surgery, Endolumenal procedures within the GI tract, Laparoscopy Laparoscopic, General surgery, Clinical leadership and excellence, Long-term Results, Endoluminal Radiofrequency Ablation of Barrett's Esopha, High-grade dysplasia HGD, Treatment of Gastroesophageal Reflux Disease GERD, Laparoscopic tools, GERD, Tightening of LES, BARRX, Unmet needs in gastrointestinal diseases, Laparoscopic or open surgical procedures, Laparoscopy Laparoscopic, Endoluminal Endolumenal Hollow Vessel, Laparoscopic fundoplication, Symptoms of GERD, Treat GERD, BARRX Halo-360 system, endoscopic suturing device, BÂRRX Medical's Ablation Systems for Barrett's Esophag, Clinical and physiologic patterns, HALO360 System, HALO90 System, Barrett's esophagus, Advanced endoscopic non-NOTES procedures, Endoscopic suturing, Massachusetts General Hospital, Endoscopy Endoscopic, Harvard Medical School, Laparoscopic technique, Laparoscopic nissen fundoplication procedure, Medical Device Development | Comments Off

EndoGastric Solutions > Results of EsophyX Multi-Center GERD Study > Transoral incisionless fundoplication surgery > No skin incisions > No cutting of vessels > No dissection of the fundus > 85% of patients remain symptom-free > Off daily GERD medication > Chanbe the dependence on pharmaceuticals

Thursday, February 28, 2008

Are the effects of daily GERD medication raising concerns that there are additional detrimental effects of pharmaceuticals that should be avoided? Is EsophyX a technology that advances the treatment of GERD forward? Is the discontinue of GERD medications especially important for women in the face of osteoporosis?

IIP > Read on here…
EndoGastric Solutions, the world leader […]

Filed in per-oral transgastric, EsophyX EndoGastric Solutions, Endoscopic suturing, Endoscopy Endoscopic, Natural Orifice Transluminal Endoscopic Surgery NOTES, EsoPhyx endoluminal fundoplication, EndoGastric Solutions Inc Redmond WA, endoscopic suturing device, EndoCinch Bard Davol Inc, StomaphyX EndoGastric Solutions, Oregon Health and Science University, Gastroesophageal reflux disease GERD, New treatment methods and devices, Gastrointestinal and Minimally Invasive Surgery GMIS, Clinical and physiologic patterns, home by the day after surgery, Reduced risk of adhesions, EndoCinch BARD Endoscopic Technologies, multiple endocinch like PTFE sutures being passed, Medical Universities Research Institutes Med Societies, Treat GERD, Less-invasive, Flexible endoscope, Bodies' natural orifices, Natural Orifice Transluminal Endoscopic Surgery, Minimally Invasive Surgery MIS, Natural orifice transluminal endoscopic surgery, Unmet needs in gastrointestinal diseases, Natural orifices such as the mouth rectum or vagina, Minimally invasive approach, Substantial learning curve, GERD, Flexible scope, Stapler for flexible endoscopes, Flexible endoscopes that have working channels, Treatment of Gastroesophageal Reflux Disease GERD, Endoluminal Endolumenal Hollow Vessel | Comments (0)

GI Sleeve Implantable weight loss device > Randomized patient blinded prospective study > Patients will receive either a device or a sham procedure > Weight loss is primary outcome measure > Duodenal—Jejunal Bypass Sleeve > Natural Orifice Transluminal Endoscopic Surgery NOTES Endobarrier Device for the Treatment of Morbid Obesity > Carolinas Medical Center > Dartmouth-Hitchcock Medical Center > Lahey Clinic Medical Center

Saturday, January 5, 2008

Does the food go on the inside of the endobarrier device with the digestive enzymes on the outside of the device? Does the endobarrier device modify metabolic pathways and prevent the mixing of food and digestive enzymes? Does the EndoBarrier stenting device migrate without safe and secure proximal fixation with T fasteners?

IIP > Read on […]

Filed in Surgical obesity intervention, Body mass index of greater than 50, Safe and secure proximal fixation, Safer alternative to gastric bypass, Food bypasses the duodenum and proximal jejunum, Investigational device, Reversible procedure, Type 2 diabetics, Experiment in treating morbid obesity, NoScarSurgeons.com, Patients Who Gain Weight After Bariatric Surgery, Endosuturing, Endobarrier device, Stented sleeve implant, Morbid obesity, Experiment in treating morbid obesity, Gastric bypass pouch and stoma reduction, Gastric bypass pouch and stoma reduction, GI Sleeve Implantable weight loss device, Endoscopic Device for the Treatment of Morbid Obesity, Metabolic disorder, Interventional, Randomized Single Blind Placebo Control Parallel Assign, Bariatric surgery, Randomized patient blinded prospective study, Overnutrition, Nutrition Disorders, Carolinas Medical Center, Dartmouth-Hitchcock Medical Center, transoral endoscopic anchor placement system, Metabolic Diseases, Lahey Clinic Medical Center, Body Weight Changes, GI Sleeve Implantable weight loss device, Reduces Size of Stomach Pouch, Weight Re-gain After Gastric Bypass, Managed care and scientific hurdles, Hybrid procedures combining endoscopy and laparoscopy, FDA regulators, Christopher C Thompson, Risk factor obesity, Innovative Hybrid T-fasteners, Tie-knot device approximates the suture ends, New suture anchor, Stapler for flexible endoscopes, Hybrid, Lee Swanstrom, Endoluminal Endolumenal Hollow Vessel, T fasteners, Leader in natural orifice surgery NOS, Food and Drug Administration FDA, Unmet needs in gastrointestinal diseases, endoluminal bariatric surgery, endoscopic gastric reduction, Obesity, Treatment Of Obesity, Body mass index, Clinical and physiologic patterns, Entrepreneurs and investors, Medical Device Company, GI Dynamics, Diabetes, Hybrid and endoluminal treatment options, endoscopically restrictive pouch similiar to surgery, endoscopic stapling system, Endoscopy Endoscopic, Intra-cavitary interventional techniques, Endoscopic suturing, Likely to be widely adopted, Hybrid Endoluminal Endolumenal Laparoscopic MIS | Comments (0)

Stented sleeve implant limits digestion > Device goes down the esophagus into the stomach > Experiment in treating morbid obesity especially in type 2 diabetics > Proximal fixation may prevent migration > Natural Orifices Endoscopic Transluminal Surgery NOTES device > Prior to gastric bypass surgery such as Roux-en-Y Gastric Bypass or Laparoscopic Adjustable Gastric Banding > EndoBarrier device > GI Dynamics

Friday, December 28, 2007

Does the food go on the inside of the endobarrier device with the digestive enzymes on the outside of the device? Does the endobarrier device modify metabolic pathways and prevent the mixing of food and digestive enzymes? Does the EndoBarrier stenting device migrate without safe and secure proximal fixation with T fasteners?

IIP > justin > […]

Filed in Digestive enzymes, Endobarrier device, Society of American Gastrointestinal and Endoscopic Sur, Incisionless Natural Orifice Surgery, Prevent the mixing of food and digestive enzymes, Stented sleeve implant, Experiment in treating morbid obesity, Experiment in treating morbid obesity, Prior too gastric bypass surgery, Surgical revision, Gastrointestinal and Minimally Invasive Surgery GMIS, scar-free surgery, Entrepreneurs and investors, Venture Capital Financing, No visible skin scar, Reduced post-operative pain, Incisionless Surgical Technique, Medical Device Company, GI Dynamics, Type 2 diabetics, Safe and secure proximal fixation, Advanced Technology Ventures, Reversible procedure, Food bypasses the duodenum and proximal jejunum, Cutlass Capital, Domain Associates, Investigational device, Polaris Venture Partners, Johnson & Johnson Development Corporation, More rapid recovery and lower cost, Applicable to wider range of patients, Roux-en-Y gastric bypass, Stented sleeve implant limits digestion, Safe and secure proximal fixation, Adjustable Gastric Banding, Hypertension and pulmonary embolus risk, Safer alternative to gastric bypass, Lining of a portion of the gastrointestinal tract, Modify metabolic pathways, Clinical and physiologic patterns, Reduced risk of adhesions, Incision-less solutions, Using transoral access, Unmet needs in gastrointestinal diseases, Minimally invasive surgery techniques, Efficacy, Flexible endoscopes that have working channels, Natural orifices such as the mouth rectum or vagina, Long-term graft performance, Less-invasive, T fasteners, No Scar Surgery, Minimally Invasive Surgery MIS, Natural Orifice Transluminal Endoscopic Surgery, Natural orifice transluminal endoscopic surgery, Bodies' natural orifices, Transoral treatment method, High blood pressure, Flexible endoscope, Food and Drug Administration FDA, Flexible scope, Natural Orifice Transgastric Endoscopic Surgery NOTES, Natural Orifice Transluminal Endoscopic Surgery NOTES, flexible endoscopic sleeve open at both ends, organ resections, Navigation inside the stomach and abdominal cavity, Diabetes, No CPT code, Likely to be widely adopted, Bariatric sleeve, endoscopic gastric reduction, Substantial learning curve, Minimally invasive approach, New suture anchor, Gastrotomy, Transluminal translumenal procedures, endoluminal bariatric surgery, Innovative Hybrid T-fasteners, Tie-knot device approximates the suture ends, Ideas For Surgery News | Comments (0)

Bovine collagen injections in the GE tract > Curon Medical’s Stretta device > NDO Plicator > Enteryx Boston Scientific > Gatekeeper Medtronic > Wilson-Cook endoscopic suturing device > EsophyX EndoGastric Solutions > What’s next?

Monday, October 22, 2007

Where are GERD therapies going from here? When will the reimbursement policies for endoluminal therapies change? Is the lack of coverage and efficacy data going to slow down the application of new techniques?

IIP > justin > ric mave:
…three different endoluminal procedures are being used…to treat GERD patients: endoscopic suturing with the NDO Plicator (NDO […]

Filed in transgastric retroperitoneal for pancreatic debridement, Natural Orifice Transluminal Endoscopic Surgery NOTES, transgastric appendectomy, transgastric endoscopic splenectomy, transgastric biliary endosurgery, transgastric tubal ligation, Natural Orifice Transgastric Endoscopic Surgery NOTES, per-oral transgastric, NDO Plicator, Wilson-Cook endoscopic suturing device, Stretta device, Bovine collagen injections in the GE tract, Navigation inside the stomach and abdominal cavity, Single incision, flexible transgasric peritoneoscopy, flexible endoscopic sleeve open at both ends, Injection of dermal bovine collagen, EsoPhyx endoluminal fundoplication, EndoCinch BARD Endoscopic Technologies, Tie-knot device approximates the suture ends, Wilson-Cook Medical Winstom Salem NC, multiple endocinch like PTFE sutures being passed, EndoGastric Solutions Inc Redmond WA, Guy-Bernard Cadiere, endoscopic gastric reduction, endoscopic stapling system, endoluminal gastric partitioning, endoscopic band ligation of esophageal varices, Innovative Hybrid T-fasteners, EsophyX EndoGastric Solutions, Endoscopic suturing, Toyooki Sonoda, Michael Li, Anthony N Kalloo, Juergen Hochberger, Dennis L Fowler,