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Category Archives: Venture Capital Financing

Novel Gastrointestinal Interventional Therapies > Endolumenal application > GI Dynamics > Gut-Lining Device > Combats Diabetes > Obesity Clinical Trial > Reduced blood sugar > More invasive procedures might carry more risk > Harvard Medical School > Reversible > Device can be retrieved via the mouth > First World Congress on Interventional Therapies for Type 2 Diabetes > EndoBarrier Gastrointestinal Liner Data > Patients with Type 2 Diabetes > Presented at the First World Congress > Interventional Therapies for Type 2 Diabetes

Thursday, September 18, 2008

Has the EndoBarrier potential to provide immediate metabolic control with less risk? Are these the most exciting and promising device data from endoscopic devices? Has this disease has reached epidemic proportions around the globe? Is there a substantial unmet need for a simple and safe approach for patients to achieve metabolic control?

IIP > read on […]

Filed in Prospective randomized sham-controlled clinical trial, Clinical-stage medical device company, Deliver immediate metabolic control, Modifying metabolic pathways, Endoluminal Therapies for Type 2 Diabetes, Keynote lecture, Novel Gastrointestinal Interventional Therapies, Lee M Kaplan, Weight Center, Orally delivered, Removable device, Health policy makers, Public health authorities and insurers, Seize the opportunity, Novel interventional therapies, Forum for the medical community, Comprehensive and multidisciplinary forum, Lines a portion of the small intestine, Top-tier investors, Catalyst Health Ventures, Treat obesity and type 2 diabetes, Noninvasive device, Domain Associates, Johnson & Johnson Development Corporation, Polaris Venture Partners, Bariatric surgery, Cutlass Capital, Advanced Technology Ventures, New York Presbyterian Hospital, Weill Cornell Medical College, GI Dynamics, Type 2 diabetes, Clinical Trial, Patients with Type 2 Diabetes, First World Congress on Interventional Therapies, Pioneering new approaches to treating metabolic disorde, Medical Device Company, EndoBarrier Gastrointestinal Liner, Gastrointestinal surgery, Resulting in weight loss, Improved glycemic control, Massachusetts General Hospital | Comments Off

Obesity and diabetes > Immediate Resolution > Type 2 Diabetes > New Study presented at the American Diabetes Association ADA > EndoBarrier > Implanted and removed endoscopically > Without need for surgical intervention > Physical barrier between ingested food and intestinal wall > Massachusetts-based GI Dynamics

Monday, June 16, 2008

How encouraging are the interim Endobarrier study results? Is the EndoBarrier’s ability to rapidly restore glycemic control reflected in the study results? Does the device mimic the metabolic effects of gastric bypass surgery without its associated complications?

IIP > read on here > http://www.primenewswire.com…
…New technology has been developed that addresses two of the biggest healthcare problems […]

Filed in Diabetes is killing about 73,000 people in the U.S. eac, Natural Orifice Trans Umbilical Surgery NOTUS, American Diabetes Association ADA, Other bariatric weight loss operations cost $25,000 in , LAGB banding costs $17,000 in the USA, Leak-proof closure, Gastroenterology, NOTES access is safe and feasible, NOTES exploration of the abdomen, no scars to remind of the operation, natural orifice, Natural orifices tranlumenal endosurgery NOTES, Laparoscopic Adjustable Gastric Banding LAGB, Natural orifice surgery appendectomy, Gastric bypass pouch and stoma reduction, Pouch enlargement or dilatation of the gastrojejunostom, Natural Orifices transgastric endoscopic surgery NOTES, Polaris Venture Partners, Johnson & Johnson Development Corporation, Metabolic Diseases, Nutrition Disorders, Bariatric surgery, Metabolic disorder, Overnutrition, Overweight, no external scars whatsoever, NOTES's going to happen relatively fast, Physical barrier, Between ingested food and intestinal wall, Without need for surgical intervention, Implanted and removed endoscopically, EndoBarrier, Massachusetts-based GI Dynamics, Development of noninvasive approaches to treat obesity, Obesity medicine, Endocrinology, Improved glycemic control, Resulting in weight loss, Designed to line a portion of the small intestine, Immediate Resolution, Obesity and diabetes, Obesity Surgery, NOSCAR research for safe adoption, No slow down in Obesity epidemic, NOTES procedure offer substantial benefits, Natural Orifice training course, NOTES Natural Orifice Translumenal Endoscopic Surgery, NOSCAR Natural Orifice Surgery Consortium for Assessmen, NOTES research, Natural Orifice Translumenal Endoscopic Surgery NOTES, Type 2 diabetes, Obesity is a complex condition, Domain Associates, Cutlass Capital, Significantly reduced level of pain and discomfort, No scar anti reflux procedure, Multi-center trial of a NOTES system, NOTES techniques, Natural orifices such as the mouth rectum or vagina, Substantial learning curve, International Conference on NOTES, Natural Orifice Transgastric Endoscopic Surgery NOTES, Potential to replace or augment current techniques, Natural Orifice Transluminal Endoscopic Surgery NOTES, Risk factor obesity, No Scar Group SAGES, Incision-less solutions, NOTES fundoplication procedure, NOTES, Way of the future, Natural orifice transluminal endoscopic surgery, NOTES & NEWS, No Scar Surgery, No-scar abdominal surgery, Bodies' natural orifices, Intentionally making gastrotomy for a cholecystectomy, Initial applications of NOTES, Viscera Stomach Colon Vagina Bladder, Per vagina, per-oral transgastric, per-anal transcolonic, Gastrotomy Closure in NOTES, Incisionless Natural Orifice Surgery, Reduces Size of Stomach Pouch, Incisionless Surgical Technique, Weight Re-gain After Gastric Bypass, Patients Who Gain Weight After Bariatric Surgery, NoScarSurgeons.com, Advanced Technology Ventures, Surgical obesity intervention, Body mass index of greater than 50, Morbid obesity, Reduced post-operative pain, No visible skin scar, Body mass index, Treatment Of Obesity, Orientation for the gastric access puncture, Navigation inside the stomach and abdominal cavity, Orientation, Obesity, home by the day after surgery, scar-free surgery, NOTES and hybrid NOTES procedures, Recovery-free surgery, Reduced risk of adhesions, Natural Orifice Transluminal Endoscopic Surgery | Comments Off

V.C.s lead Spin-Off of Boston Scientific Unit > TriVascular2 > Divest nonstrategic assets > $65 million from previous and new investors > Series A preferred round to finance spinout > Programs Boston Scientific suspended in June 2006 > MPM Capital > New Enterprise Associates > Delphi Ventures > Kearny Venture Partners > Complete clinical development > Endovascular aneurysm repair EVAR > Stent-graft

Thursday, April 3, 2008

Does TriVascular address an opportunity that justifies the new investments by MPM Capital and NEA? Is it feasible to address a broader patient population requiring endovascular repair of aortic aneurysms with the novel stent-graft from TriVascular? Will these patients have a safe and permanent alternative to open surgical repair?

IIP > Read on here…
TriVascular2, a company […]

Filed in Stent graft migration following endovascular aneurysm r, Aorfix Dacron stent-graft, Type I endoleaks, Aneurysm rupture, Paraplegia secondary to spinal cord ischaemia, Endovascular techniques prone to similar complications, Surgical revision, GORE EXCLUDER AAA Endoprosthesis, Stent grafts have a tendency to migrate, Fixation of stent grafts, Endoleaks, Keep the graft in place, Life Line Screening, Benefit from screening, Complication of stent-graft repair, Men in England are to be offered AAA screening, New Enterprise Associates, MPM Capital, Kearny Venture Partners, Complete clinical development, Stent-graft, Endovascular aneurysm repair EVAR, Divest nonstrategic assets, Finance spinout, Spin-Off, Delphi Ventures, Boston Scientific Unit, TriVascular2, Series A preferred round, Medical devices to treat aneurysms AAA, Stent graft fixation product, Stent Stapler, Watchful waiting, Treatment of aneurysms, Open aneurysm repair, Surgical aneurysm repair, Endoaneurysmorrhaphy, Elective surgical treatment of AAA, Albert Einstein, Sudden severe back or abdominal pain, Ultrasound screening, Rupture of an abdominal aortic aneurysm, Abdominal aortic aneurysm AAA, Endovascular stent graft, Risk of developing AAA, Silent killer, Totally laparoscopic AAA replacement, Larger aneurysms can leak or rupture, Free screening for AAA, Ascending aortic aneurysm, Welcome to Medicare physical, Screen the aorta, Stapling may replace stitching, Scanning and visualizing the aorta, Simple $50 ultrasound scan, Stent-graft technology under serious scrutiny, Need for reintervention, Endovascular stenting, Long-term graft performance, AAA stent-graft device, Subsidiary of a major stent-graft company, Warning letter, Ideas For Surgery News | Comments (0)

ProDisc Spine-disk marketers > Attorney general probe > Subpoenas two companies > Viscogliosi Brothers > Spine Solution Inc > Synthes-Stratec > Over financing > Investment funds for Medical device development > Open for spine surgeons > Venture capital > Chain of M&A > Industry spin-off

Wednesday, March 5, 2008

What is the role of investment funds in medical device development? Are investments of surgeons who are also medical device investigators an appropriate source for venture capital? Will yet another group of shareholders and investors be added to the marketing history of the semi-constrained Prodisc design from the inventor Dr Thierry Marnay to JBS Edwards […]

Filed in Synthes Spine, ProDisc Semi-constrained design, Viscogliosi Brothers, Implanted between two vertebrae, Subpoenas, JBS Edwards, B Braun, Aesculap, Start-up money for development, Investment funds, Spine-disk makers, Spine Solution, Thierry Marnay, Venture Capital Financing | Comments (0)

Move a device idea from the research phase to the market > Massachusetts medical device industry > Industry-specific support > Innovation Index of the Massachusetts Economy > Massachusetts Biomedical Initiatives > Dow Jones VentureSource > Massachusetts Technology Collaborative’s John Adams Innovation Institute > Worcester business incubators

Wednesday, February 13, 2008

Is Massachusetts a Medtech hub that benefits from industry that has developed there close to all the universities? Is the infrastructure for both the creation of device ideas and the development of device ideas unique to the state of Massachusetts? Why can medical device companies gain a foothold in Massachusetts that they cannot gain elsewhere?

IIP […]

Filed in Massachusetts medical device industry, BioVentures Investors, Medical device bill, Crescent Innovations Inc, Polymer injected into the body to reduce inflammation, TMJ pain treatment, AcroMIS LLC, Industry-specific support, Mount Auburn Hospital, McLean Hospital, Schepens Eye Research Institute, Spaulding Rehabilitation Hospital, Medical device business incubators, VA Boston, Entegrion's Stasilon, Wound care, Move a device idea from the research phase to the marke, Corporate partnerships, Innovation Index of the Massachusetts Economy, Massachusetts Biomedical Initiatives, Worcester business incubators, John Adams Innovation Institute, Angel groups, Detect the nuclei of atoms, Plastics injection molding, Nypro Inc, HydroCision Inc, Water-jet tools for surgeons, Nuclear resonance technology, SIV Technologies Inc, Massachusetts General Hospital, Massachusetts Eye and Ear Infirmary, Innovative technology, Start-up companies, Endoscopy Endoscopic, Boston Scientific, Venture Capital Financing, Initial Public Offering IPO, Food and Drug Administration FDA, Innovative products, Flexible endoscope, Laparoscopy Laparoscopic, Disclosing new technology and innovations, Medical Universities Research Institutes Med Societies, New product development, Endovascular stent graft, Entrepreneurs and investors, Medical Device Company, Forsyth Institute, Dana-Farber Cancer Institute, Harvard Pilgrim Health Care, Joslin Diabetes Center, Immune Disease Institute, Judge Baker Children's Center, Children's Hospital Boston, Cambridge Health Alliance, Drug eluting stents, Investigational device, Boston University Medical Center, US Healthcare is the largest industry in the United Sta, Brigham and Women's Hospital, Harvard Medical School, Medical Device Development | Comments (0)

Safe Veres Needle Technique > Aragon Surgical LapCap > Establish Fast And Safe Pneumoperitoneum In Laparoscopic Surgery > Medical Device Startup > Aragon Surgical Inc > Raised $25 Million Venture Capital In A Series B Round

Monday, February 11, 2008

Will Aragon Surgical Inc be successful in developing a platform of surgical products which offer unique value propositions to surgeons, patients, and operating facilities? Will Aragon have five products on the market within two years? Will Aragon’s mission statement to save money and increase margins for hospitals prevail and how will the company reduce costs […]

Filed in Stanford University Medical School, Viability of technology, Radio frequency technology, Onset Ventures, Integral Capital Partners, Delphi Ventures, Early regulatory trials, VeriSure Inc, Increasing focus of hospitals, Improve patient outcomes, Reducing operating room time, Reducing costs by speeding up surgeries, All-stock deal from angel investors, Radio frequency energy to create and seal incisions, Bay City Capital, Unique value propositions, Medical Device Company, Establish fast and safe Pneumoperitoneum, Venture Capital Financing, Laparoscopic technique, Laparoscopic tools, Laparoscopy, Aragon Surgical LapCap, Aragon Surgical Inc, Tools that seal and divide tissue, Cutting time, Safe Verres Needle Technique, Aragon Surgical LapCap, Medical device startup, Raised $25 million in a Series B round, Laparoscopy Laparoscopic | Comments (0)

Stented sleeve implant limits digestion > Device goes down the esophagus into the stomach > Experiment in treating morbid obesity especially in type 2 diabetics > Proximal fixation may prevent migration > Natural Orifices Endoscopic Transluminal Surgery NOTES device > Prior to gastric bypass surgery such as Roux-en-Y Gastric Bypass or Laparoscopic Adjustable Gastric Banding > EndoBarrier device > GI Dynamics

Friday, December 28, 2007

Does the food go on the inside of the endobarrier device with the digestive enzymes on the outside of the device? Does the endobarrier device modify metabolic pathways and prevent the mixing of food and digestive enzymes? Does the EndoBarrier stenting device migrate without safe and secure proximal fixation with T fasteners?

IIP > justin > […]

Filed in Digestive enzymes, Endobarrier device, Society of American Gastrointestinal and Endoscopic Sur, Incisionless Natural Orifice Surgery, Prevent the mixing of food and digestive enzymes, Stented sleeve implant, Experiment in treating morbid obesity, Experiment in treating morbid obesity, Prior too gastric bypass surgery, Surgical revision, Gastrointestinal and Minimally Invasive Surgery GMIS, scar-free surgery, Entrepreneurs and investors, Venture Capital Financing, No visible skin scar, Reduced post-operative pain, Incisionless Surgical Technique, Medical Device Company, GI Dynamics, Type 2 diabetics, Safe and secure proximal fixation, Advanced Technology Ventures, Reversible procedure, Food bypasses the duodenum and proximal jejunum, Cutlass Capital, Domain Associates, Investigational device, Polaris Venture Partners, Johnson & Johnson Development Corporation, More rapid recovery and lower cost, Applicable to wider range of patients, Roux-en-Y gastric bypass, Stented sleeve implant limits digestion, Safe and secure proximal fixation, Adjustable Gastric Banding, Hypertension and pulmonary embolus risk, Safer alternative to gastric bypass, Lining of a portion of the gastrointestinal tract, Modify metabolic pathways, Clinical and physiologic patterns, Reduced risk of adhesions, Incision-less solutions, Using transoral access, Unmet needs in gastrointestinal diseases, Minimally invasive surgery techniques, Efficacy, Flexible endoscopes that have working channels, Natural orifices such as the mouth rectum or vagina, Long-term graft performance, Less-invasive, T fasteners, No Scar Surgery, Minimally Invasive Surgery MIS, Natural Orifice Transluminal Endoscopic Surgery, Natural orifice transluminal endoscopic surgery, Bodies' natural orifices, Transoral treatment method, High blood pressure, Flexible endoscope, Food and Drug Administration FDA, Flexible scope, Natural Orifice Transgastric Endoscopic Surgery NOTES, Natural Orifice Transluminal Endoscopic Surgery NOTES, flexible endoscopic sleeve open at both ends, organ resections, Navigation inside the stomach and abdominal cavity, Diabetes, No CPT code, Likely to be widely adopted, Bariatric sleeve, endoscopic gastric reduction, Substantial learning curve, Minimally invasive approach, New suture anchor, Gastrotomy, Transluminal translumenal procedures, endoluminal bariatric surgery, Innovative Hybrid T-fasteners, Tie-knot device approximates the suture ends, Ideas For Surgery News | Comments (0)

Evalve Completes $60 Million Series D Financing > MitraClip Device > Percutaneous repair of cardiac valves > Device for Percutaneous Repair of Mitral Valve Regurgitation > EVEREST Pivotal Study

Thursday, November 29, 2007

Are serial entrepreneurs and VC’s focused on investing even more into Evalve for finally taking the company through the process of innovation to a point of actual value creation? Is Evalve Inc.’s new round of financing a true indication for the high expectations of its investors? Is the participation of Emergent Medical Ventures, the new […]

Filed in Percutaneous Repair of Mitral Valve Regurgitation, Percutaneous repair of cardiac valves, EVEREST Pivotal Study, Entrepreneurs and investors, Allan May, Thomas Fogarty, MitraClip Device, Venture Capital Financing, Minimally invasive approach, Minimally invasive surgery techniques, Cardiovascular devices, Percutaneous approach, Evalve, Minimally Invasive Surgery MIS | Comments (0)